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KMID : 0363320220430061122
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Journal of Korean Oriental Internal Medicine
2022 Volume.43 No. 6 p.1122 ~ p.1133
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An Exploratory Study of the Effect of Ongyeong-tang Administration on Insomnia Disorder in Patients with Neurological Diseases: A Retrospective Chart Review Study
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Kwon Seung-Won
Lee Han-Gyul
Jung Woo-Sang
Mun Sang-Kwan
Cho Ki-Ho
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Abstract
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Objectives:The aim of this study was to retrospectively evaluate the efficacy and safety of Ongyeong-tang (OGT) in the treatment of insomnia in patients afflicted with neurological diseases, according to the medical records of one medical institution. OGT is a herbal prescription that originates from the “Synopsis of Prescriptions of the Golden Chamber” and has been used for menopausal symptoms, uterine diseases, skin diseases, insomnia, and other neuropsychiatric symptoms.
Methods:Medical records of patients who visited Kyung Hee University Korean Medicine Hospital from January 1, 2021 to June 30, 2022, received outpatient or inpatient treatment, and met the inclusion criteria were used in this study.
Results:Twenty-four patients satisfied the inclusion criteria and were included. The Pittsburgh Sleep Quality Index-Korean version (PSQI-K) score was used to evaluate the outcomes before and after treatment. After an average of 14.42±9.2 days of OGT extract intake, 20 patients (83.3%) experienced improvement. The remaining four (16.7%) had no change in their symptoms, but none demonstrated worsening of symptoms. The total PSQI-K score showed a statistically significant decrease from 13.08±4.54 to 10.42±4.58 (p<0.001). Sleep quality, sleep duration, sleep disturbance, use of sleeping medications, and daytime dysfunction also showed statistically significant improvements.
Conclusions:Administration of OGT extract may be a relatively safe and effective therapeutic option for insomnia in patients with neurological diseases.
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KEYWORD
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Ongyeong-tang, Wenjingtang, Unkeito, insomnia disorder, neurological diseases
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